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Journal > MAKARA of Health Series > AKTIVITAS KEMOPREVENSI EKSTRAK TEMU MANGGA

 

MAKARA of Health Series
##issue.vol## 9, ##issue.no## 2 (2005): December
AKTIVITAS KEMOPREVENSI EKSTRAK TEMU MANGGA
Article Info   ABSTRACT
Published date:
14 Oct 2010
 
Chemoprevention Activity of Temu Mangga Extracts. The chemoprevention activity of temu mangga extracts wasinvestigated by determination of antioxidant activity with a peroxidation number method and gluthatione-S-transferase(GST) activity in Chang medium culture and cell lysate (total GST activity). The results indicated that ethanol extracthas a strong antioxidant activity. It is caused by the phenolic group in the ethanol extract. Treatment Chang cellculture with 7th and 4th ethanol fractions increased the GST activity when compared to the control. The total GSTactivity (cytosolic and microsomal) increased when Chang cell culture was treated with H2O2/Fe+2. The decrease of thetotal GST activity was observed when 7th and 4th ethanol fractions were supplemented with H2O2/Fe+2 compared to thecell culture receiving H2O2/Fe+2 only.Keywords: antioxidant activity, Curcuma mangga, gluthatione-S-transferase, Chang cell culture
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