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Journal > Jurnal Penyakit Dalam Indonesia > Pendekatan Diagnosis dan Tata Laksana Alergi Obat

 

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Jurnal Penyakit Dalam Indonesia
Vol 4, No 1 (2017)
Pendekatan Diagnosis dan Tata Laksana Alergi Obat
Article Info   ABSTRACT
Published date:
30 Mar 2017
 
Alergi obat merupakan salah satu masalah kesehatan yang cukup serius. Alergi obat dapat didefinisikan sebagai reaksi simpang obat yang melibatkan mekanisme imunologis. Meskipun demikian, tidak mudah menentukan apakah suatu reaksi simpang obat merupakan reaksi alergi dan dibutuhkan suatu pendekatan diagnosis yang sistematis. Selain anamnesis, pemeriksaan fisis, pemeriksaan penunjang alergi obat yang terdiri dari pemeriksaan penunjang umum dan khusus yang dapat dilakukan baik in vivo, in vitro, maupun dengan biopsi. Tata laksana alergi obat adalah menghindari faktor yang menimbulkan gejala, mengobati reaksi secara benar dan cara-cara khusus seperti threating through, tes dosing, desensitisasi dan pramedikasi terhadap obat-obat tertentu.Kata Kunci: alergi, diagnosis,obat, tata laksana√ā¬†Approach to Diagnosis and Treatment of Drug AllergyDrug allergy is a serious medical problem. Drug allergy can be defined as an adverse drug reaction involving immunological mechanism. However, it is not easy to decide whether an adverse drug reaction is an allergic reaction, and it requires a systematically diagnostic approach. Beside a thorough history taking and physical examination, there are general and specific laboratory examination to investigate drug allergy which can be done in vivo, in vitro, or biopsy. The management of drug allergy include the avoidance of the precipitating event, and specific methods to reduce the drug reaction which include threating through, dosing test, desensitization, and the administration of premedication for certain drugs.
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