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Journal > Dentistry e-Journal FKG USU > PENGARUH PASTA GIGI MENGANDUNG KITOSAN BLANGKAS BERMOLEKUL TINGGI TERHADAP PERTUMBUHAN STREPTOCOCCUS MUTANS

 

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Dentistry e-Journal FKG USU
Vol 1
PENGARUH PASTA GIGI MENGANDUNG KITOSAN BLANGKAS BERMOLEKUL TINGGI TERHADAP PERTUMBUHAN STREPTOCOCCUS MUTANS
dominika, dennis ( Universitas Sumatera Utara)
Article Info   ABSTRACT
Published date:
01 Feb 2013
 
Dental caries is a disease of the mineralized tissue of the teeth, caused by the action of microorganisms on fermentable carbohydrate. Streptococcus mutans is the bacteria which plays a vital role on the caries process. Brushing teeth twice a day with appropriate dentifrice is a rational choice for preventing caries disease. Chitosan is derived from deacetilation of chitin with concentrated NaOH solution. The aim of this study is to compare antibacterial effect between dentifrices containing horseshoe crab’s high molecular chitosan (tested material), commercial dentifrice and placebo dentifrice against bacterial growth of Streptococcus mutans cultivated on NA medium. Antibacterial materials are divided into 5 groups: group I dentifrice containing horseshoe crab’s high molecular chitosan 0,5 %; group II 1,5%; group III 2,5%; group IV commercial dentifrice  (NaMFP) as control (+) and group V placebo dentifrice as control (-). The results of the study after 24 hours showed that the largest inhibition zone was the group I 0,5 % > placebo dentifrice > group II 1,5% > Group III 2,5% > commercial dentifrice. The results of one way ANOVA showed a significant difference between the groups of dentifrice containing horseshoe crab’s chitosan 0,5%; 1,5%; 2,5%; placebo dentifrice and commercial dentifrice to inhibit the growth of Streptococcus mutans. In conclusion, dentifrice containing horseshoe crab’s high molecular chitosan can inhibit the growth of Streptococcus mutans with larger inhibition zone  compared with commercial dentifrice. Key words: caries, Streptococcus mutans, dentifrice, chitosan
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