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Journal > C H E M I C A > Aktivitas Anti-Leukemia Senyawa Oleanan Dari Kayu Akar Tumbuhan Pterospermum Subpeltatum C.B.Rob

 

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C H E M I C A
Vol 12, No 1 (2011)
Aktivitas Anti-Leukemia Senyawa Oleanan Dari Kayu Akar Tumbuhan Pterospermum Subpeltatum C.B.Rob
Article Info   ABSTRACT
Published date:
04 Apr 2013
 
ABSTRAK Telah diisolasi satu senyawa turunan triterpenoid yaitu olean -12-en-2,3,23-triol-28-oat dari fraksi kloroform kayu akar Pterospermum subpeltatum C.B. Rob (Sterculiaceae) .Elusidasi  struktur berdasarkan data spektroskopi IR, 1H dan              13C-NMR. Senyawa ini menunjukkan aktivitas biologis terhadap sel murin leukemia P-388 dengan nilai  IC50 : 58 μg/mL. Kata kunci: Pterospermum subpeltatum C.B.Rob, olean-12-en-2,3,23-triol-28-oat, sel tumor P-388 ABSTRACT Isolation of a derivative triterpenoid compound, oleane-12-en-2,3,23-triol-oate from the chloroform fraction of the root wood of P.subpeltatum (Sterculiaceae). The structure elucidation is based on spectroscopic data of IR,  1 H dan  13C-NMR.The Oleane compound which has been isolated, showed biological activity to wards murine leukemia P-388 cells IC50 value 58 μg/mL. Keyword: Pterospermum subpeltatum C.B.Rob, olean-12-en-2,3,23-triol-28-oat, sel tumor P-388
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