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Journal > Jurnal Bahan Alam Indonesia > OLEANEN DARI TUMBUHAN Pterospermumcelebicum Miq. SERTA SIFAT SITOTOKSIKNYA TERHADAP SEL MURIN LEUKEMIA P-388

 

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Jurnal Bahan Alam Indonesia
Vol 7, No 3 (2010)
OLEANEN DARI TUMBUHAN Pterospermumcelebicum Miq. SERTA SIFAT SITOTOKSIKNYA TERHADAP SEL MURIN LEUKEMIA P-388
Marzuki, Asnah ( Fakultas Farmasi, Lab Kimia Farmasi, Universitas Hasanuddin, Makassar.)
Noor, Alfian ( Fakultas MIPA Jurusan Kimia, Universitas Hasanuddin, Makasar.)
Soekamto, Nunuk ( Fakultas MIPA Jurusan Kimia, Universitas Hasanuddin, Makasar.)
Harlim, Tjodi ( Fakultas MIPA Jurusan Kimia, Universitas Hasanuddin, Makasar.)
Article Info   ABSTRACT
Published date:
15 Jan 2013
 
Olean-12-en-2-3-diol-28-oic acid has been isolated from the ethyl acetate extract of Pterospermum celebicum Miq (Sterculiaceae) heartwood. The structure of the compound was established based on spectroscopic  evidence, including UV, FTIR, 1H NMR, 13C NMR, COSY and HMBC spectra and by comparing with reported data. Cytotoxity of the isolated compound against murine leukemia – 388 cells showed their IC50 valurs was 15,0 μg/ml.
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