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Journal > Jurnal Bahan Alam Indonesia > BIOAKTIVITAS ANTIKANKER DAN ELUSIDASI STRUKTUR SENYAWA ASAM 2,3,23-TRIHIDROKSI-12-OLEANEN-28-OAT DARI TUMBUHAN PTEROSPERMUM CELEBICUM MIQ.

 

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Jurnal Bahan Alam Indonesia
Vol 7, No 4 (2010)
BIOAKTIVITAS ANTIKANKER DAN ELUSIDASI STRUKTUR SENYAWA ASAM 2,3,23-TRIHIDROKSI-12-OLEANEN-28-OAT DARI TUMBUHAN PTEROSPERMUM CELEBICUM MIQ.
Marzuki, Asnah ( Fakultas Farmasi, Lab Kimia Farmasi, Universitas Hasanuddin.)
Noor, Alfian ( Fakultas MIPA, Jurusan Kimia, Universitas Hasanuddin.)
Soekamto, Nunuk ( Fakultas MIPA, Jurusan Kimia, Universitas Hasanuddin.)
Harlim, Tjodi ( Fakultas MIPA, Jurusan Kimia, Universitas Hasanuddin.)
Article Info   ABSTRACT
Published date:
15 Jan 2013
 
Bioactivity test and molecular structure elucidation of a chloroform extract from heartwood of Pterospermum celebicum Miq have been carried out. After extraction, fractination and purification, isolated extract was tested with Murine cell P-388 for its toxicity. Its chemicla structure was examined using various spectroscopic methods such as IR, NMR, COSY and HMBC and it was conluded that this compound was 2,3,23 trihydroxy-2-oleanen-29-oic acid with IC50 56.0 μg/ml. Further research will be needed towards its application as anti cancer drug.
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