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Journal > Jurnal Bahan Alam Indonesia > EPIDIOKSI STEROL, SENYAWA ANTIBAKTERI DARI SPON LAUT Petrosia nigrans

 

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Jurnal Bahan Alam Indonesia
Vol 7, No 6 (2011)
EPIDIOKSI STEROL, SENYAWA ANTIBAKTERI DARI SPON LAUT Petrosia nigrans
Handayani, Dian ( Fakultas Farmasi Universitas Andalas Padang)
Sayuti, Noviyandi ( Fakultas Farmasi Universitas Andalas Padang)
Dachriyanus, . ( Fakultas Farmasi Universitas Andalas Padang)
van Soest, Rob W.M ( Inst Voor Systematick en Populatie Biologie, Zoologisch Museum in Amsterdam.)
Article Info   ABSTRACT
Published date:
15 Jan 2013
 
A sterol compound, 5,8-epidioxy-24-etilkolest-6-en-3-ol has been isolated from n-hexane fraction of methanolic extract of marine sponge Petrosia nigrans. The structure of the isolated compound was determined based on spectroscopic data, including IR and NMR spectra. The compound showed antibacterial activity with MIC (Minimum  Inhibitory Concentration) 50 ppm against Staphylococcus aureus, 100 ppm against Pseudomonas auruginosa and Escherichia coli.
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